PRIMER ON THE RHEUMATIC DISEASES

New and expanded chapters heighten the translational nature of the book
Color figures depict cutaneous findings and histopathology
An entire section devoted to juvenile inflammatory arthritis

Arthritis and other rheumatic diseases are a leading cause of disability and affect more than 46 million Americans (including 300,000 children). The Primer is designed to provide up-to-date information about the major clinical syndromes. It is one of the most prestigious and comprehensive texts on arthritis and related diseases, including osteoarthritis, rheumatoid arthritis, osteoporosis, lupus and more than one hundred others. It offers medical students and physicians a concise description of the current science, diagnosis, clinical consequences, and principles of management.

Now entering its eighth decade, the 13th Edition of The Primer strongly rejects the notion “If it ain’t broke, don’t fix it”. New and expanded chapters heighten the translational nature of this edition, and color figures depict cutaneous findings and histopathology.

In view of the recent remarkable strides in understanding and treating rheumatic disease, students, trainees, and practicing clinicians all need a standard textbook that can change with the times and reflect these advances. The Primer continues to fill that need.

Written for:

Medical students and physicians

Keywords:

Orthopedics

Table of contents

Foreword by Michael E. Weinblatt
Preface
Contributors

1. Public Health and Arthritis: A Growing Imperative - Patience H. White and Rowland W. Chang

2. Evaluation of the Patient

A. History and Physical Examination - David B. Robinson and Hani S. El-Gabalawy
B. Laboratory Assessment - Kerstin Morehead
C. Arthrocentesis, Synovial Fluid Analysis, and Synovial Biopsy - Kenneth H. Fye
D. Imaging of Rheumatologic Diseases - William W. Scott, Jr., William J. Didie, and Laura M. Fayad

3. Musculoskeletal Signs and Symptoms

A. Monarticular Joint Disease - H. Ralph Schumacher and Lan X. Chen
B. Polyarticular Joint Disease - Sterling West
C. Neck and Back Pain - David Borenstein
D. Regional Rheumatic Pain Syndromes - Joseph J. Biundo, Jr.
E. The Fibromyalgia Syndrome - Dina Dadabhoy and Daniel J. Clauw

4. Molecular and Cellular Basis of Immunity and Immunological Diseases - Kevin Elias, Richard Siegel, and John J. O’Shea

5. Genetics and Disease - James Kelley and Robert P. Kimberly

6. Rheumatoid Arthritis

A. Clinical and Laboratory Manifestations
B. Epidemiology, Pathology, and Pathogenesis - Jean-Marc Waldenburger and Gary S. Firestein
C. Treatment and Assessment - Alyce M. Oliver and E. William St. Clair

7. Juvenile Idiopathic Arthritis

A. Clinical Features - Daniel J. Lovell
B. Pathology and Pathogenesis - Patricia Woo
C. Treatment and Assessment - Philip J. Hashkes and Ronald M. Laxer
D. Special Considerations - Carol B. Lindsley

8. Psoriatic Arthritis

A. Clinical Features - Dafna D. Gladman
B. Pathology and Pathogenesis - Christopher Ritchlin
C. Treatment and Assessment - Philip J. Mease

9. Ankylosing Spondylitis

A. Clinical Features - Désirée Van der Heijde
B. Pathology and Pathogenesis - Juergen Braun
C. Treatment and Assessment - John C. Davis, Jr.

10. Reactive and Enteropathic Arthritis - Robert D. Inman

11. Osteoarthritis

A. Clinical Features - Paul Dieppe
B. Pathology and Pathogenesis - Francis Berenbaum
C. Treatment - Leena Sharma

12. Gout

A. Clinical Features - N. Lawrence Edwards
B. Epidemiology, Pathology, and Pathogenesis - Hyon K. Choi
C. Treatment - Robert A. Terkeltaub

13. Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals - Geraldine McCarthy

14. Infectious Disorders

A. Septic Arthritis - George Ho, Jr.
B. Viral Arthritis - Leonard H. Calabrese
C. Lyme Disease - Linda K. Bockensted
D. Mycobacterial, Fungal, and Parasitic Arthritis - Steven R. Ytterberg
E. Rheumatic Fever - Stanford Shulman and Preeti Jaggi

15. Systemic Lupus Erythematosus

A. Clinical and Laboratory Features - Jill P. Buyon
B. Epidemiology, Pathology, and Pathogenesis - David S. Pisetsky
C. Treatment and Assessment - Susan Manzi and Amy H. Kao

16. Antiphospholipid Syndrome - Michelle Petri

17. Systemic Sclerosis

A. Clinical Features - Maureen D. Mayes
B. Epidemiology, Pathology, and Pathogenesis - John Varga
C. Treatment and Assessment - Maya H. Buch and James R. Seibold

18. Idiopathic Infl ammatory Myopathies

A. Clinical Features - Robert L. Wortmann
B. Pathology and Pathogenesis - Lisa G. Rider and Frederick W. Miller
C. Treatment and Assessment - Chester V. Oddis

19. Metabolic Myopathies - Alan N. Baer

20. Sjögren’s Syndrome - Troy Daniels

21. Vasculitides

A. Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu’s Arteritis - Cornelia M. Weyand and Jörg J. Goronzy
B. Polyarteritis Nodosa - Keith T. Rott
C. The Antineutrophil Cytoplasmic Antibody–Associated Vasculitides: Wegener’s Granulomatosis, Microscopic Polyangiitis, and the Churg–Strauss Syndrome - John H. Stone
D. Immune Complex–Mediated Vasculitis - Philip Seo
E. Miscellaneous Vasculitis (Behçet’s Disease, Primary Angiitis of the Central Nervous System, Cogan’s Syndrome, and Erythema Elevatum Diutinum) - Kenneth T. Calamia and Carlo Salvarani
F. Kawasaki’s Disease

22. Relapsing Polychondritis - Harvinder S. Luthra

23. Adult-Onset Still’s Disease - John M. Esdaile

24. Periodic Syndromes - John G. Ryan and Daniel L. Kastner

25. Less Common Arthropathies

A. Hematologic and Malignant Disorders - Adel G. Fam
B. Rheumatic Disease and Endocrinopathies - Peter A. Merkel
C. Hyperlipoproteinemia and Arthritis - Robert F. Spiera
D. Neuropathic Arthropathy - Ann K. Rosenthal
E. Dermatologic Disorders - Jeffrey P. Callen
F. Hypertrophic Osteoarthropathy - Manuel Martinez-Lavin

26. Complex Regional Pain Syndrome - Geoffrey Littlejohn

27. Sarcoidosis - Edward S. Chen

28. Storage and Deposition Diseases - Duncan A. Gordon

29. The Amyloidoses - Pasha Sarraf and Jonathan Kay

30. Neoplasms of the Joint - Andrew J. Cooper, James D. Reeves, and Sean P. Scully

31. Heritable Disorders of Connective Tissue - Reed Edwin Pyeritz

32. Bone and Joint Dysplasias - William A. Horton

33. Osteonecrosis - Thorsten M. Seyler, David Marker, and Michael A. Mont

34. Paget’s Disease of Bone - Roy D. Altman

35. Osteoporosis

A. Epidemiology and Clinical Assessment - Kenneth G. Saag
B. Pathology and Pathophysiology - Philip Sambrook
C. Treatment of Postmenopausal Osteoporosis - Nelson B. Watts

36. Rehabilitation of Patients with Rheumatic Diseases - Thomas D. Beardmore

37. Psychosocial Factors in Arthritis - Alex Zautra and Denise Kruszewski

38. Self-Management Strategies - Teresa J. Brady

39. Pain Management - John B. Winfi eld

40. Therapeutic Injections of Joints and Soft Tissues - Juan J. Canoso

41. Nonsteroidal Anti-Infl ammatory Drugs - Leslie J. Crofford

42. Glucocorticoids - Frank Buttgereit and Gerd-Rüdiger Burmester

43. Operative Treatment of Arthritis - Joseph A. Buckwalter and W. Timothy Ballard

44. Complementary and Alternative Therapies - Erin L. Arnold and William J. Arnold

Appendix I. Criteria for the Classifi cation and Diagnosis of the Rheumatic Diseases

Appendix II. Guidelines for the Management of Rheumatic Diseases

Appendix III. Supplement and Vitamin and Mineral Guide

Index