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DESCRIPTION
Easily accessibleand clinically focused, Abeloff's Clinical Oncology, 6th Edition,covers recent advances in our understanding of the pathophysiologyof cancer, cellular and molecular causes of cancer initiationand progression, new and emergingtherapies, current trials, and muchmore. Masterfully authoredby an international team of leading cancerexperts, it offers clear, practical coverage of everything frombasic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up.
TABLE OF CONTENTS
PART I: SCIENCEAND CLINCIAL ONCOLOGY
SECTION A: BIOLOGYAND CANCER
1. Molecular Tools in Cancer Research
2. Intracellular Signaling
3. The CellularMicroenvironment and Metastases
4. Control of theCell Cycle
5. The Pathophysiologyof Cancer Cell Death
6. Cancer Immunology
7. Stem Cells,Cell Differentiation, and Cancer
8. Vascular and Interstitial Biology of Tumors
9. Cancer Metabolism
SECTION B: GENESISOF CANCER
10. Environmental Factors
11. DNA DamageResponse Pathways and Cancer
12. Viruses andHuman Cancer
13. Genetic Factors:Hereditary Cancer Predisposition Syndromes
14. Genetic andEpigenetic Changes in Cancer
SECTION C: DIAGNOSIS OF CANCER
15. Pathology, Biomarkers,and Molecular Diagnostics
16. Imaging
SECTION D: CLINICALTRIALS
17. Biostatistics and Bioinformatics in Clinical Trials
18. Trial Design
19. Structures SupportingCancer Clinical Trials
20. Oncology andHealth Care Policy
SECTION E: PREVENTIONAND EARLY DETECTION
21. Discovery and Characterization of Cancer Genetic Susceptibility Alleles
22. Lifestyle andCancer Prevention
23. Cancer Screeningand Early Detection
24. Nicotine Dependence:Current Treatments and Future Directions
SECTION F: TREATMENT
25. Cancer Pharmacology
26. Therapeutic Targeting of CancerCells: Era of Molecularly Targeted Agents
27. Basics ofRadiation Therapy
28. Hematopoietic Stem Cell Transplantation
29. Gene Therapy in Oncology
30. Therapeutic Antibodies and Immunologic Conjugates
31. Complementary and Alternative Medicine
PART II:PROBLEMS COMMON TO CANCER ANDTHERAPY
SECTION A: HEMATOLOGICPROBLEMS AND INFACTIONS
32. Disorders ofBlood Cell Production in Clinical Oncology
33. Diagnosis, Treatment, and Prevention of Cancer-RelatedVenous Thrombosis
34. Infection in the Patient withCancer
SECTION B: SYMPTOMMANAGEMENT
35. Hypercalcemia
36. Tumor Lysis Syndrome
37. Cancer-RelatedPain
38. Cancer Cachexia
39. Nausea and Vomiting
SECTION C: TREATMENTCOMPLICATIONS
40. Oral Complications
41. Dermatologic Toxicities of AnticancerTherapy
42. Cardiovascular Effects of Cancer Therapy
43. Reproductive Complications
44. Paraneoplastic Neurologic Syndromes
45. Neurologic complications
46. Endocrine Complications
47. Pulmonary Complicationsof Anticancer Treatment
SECTION D: POST TREATMENT CONSIDERATIONS
48. Rehabilitation of Individuals with Cancer
49. Survivorship
50. Second MalignantNeoplasms
51. Caring forPatients at the End of Life
SECTION E: LOCAL EFFECTS OF CANCERAND ITS METASTASIS
52. Acute Abdomen, Bowel Obstruction, and Fistula
53. Superior Vena Cava Syndrome
54. Spinal CordCompression
55. Brain Metastasesand Neoplastic Meningitis
56. Bone Metastases
57. Lung Metastases
58. Liver Metastases
59. Malignancy-RelatedEffusions
SECTION F: SPECIALPOPULATIONS
60. Cancer in theElderly: Biology, Prevention, and Treatment
61. Special Issuesin Pregnancy
62. Human Immunodeficiency Virus(HIV) Infection and Cancer
PART III:SPECIFIC MALIGNANCIES
SECTION A
63. Cancer ofthe Central Nervous System
SECTION B
64. Ocular Tumors
65. Cancer ofthe Head and Neck
SECTION C: SKIN
66. Melanoma
67. Nonmelanoma Skin Cancers: Basal Cell and Squamous CellCarcinomas
SECTION D: ENDOCRINE
68. Cancer ofthe Endocrine System
SECTION E: THORACIC
69. Cancer ofthe Lung: Non-Small Cell Lung Cancer and Small CellLung Cancer
70. Diseases ofthe Pleura and Mediastinum
71. Cancer ofthe Esophagus and Gastroesophageal Junction
SECTION F: GASTROINTESTINAL
72. Cancer ofthe Stomach and Gastroesophageal Junction
73. Cancer ofthe Small Bowel
74. Colon Cancer
75. Cancer ofthe Rectum
76. Cancer ofthe Anal Canal
77. Liver and BileDuct Cancer
78. Carcinoma of the Pancreas
SECTION G: GENITOURINARY
79. Cancer ofthe Kidney
80. Carcinoma of the Bladder
81. Prostate Cancer
82. Cancer ofthe Penis
83. Testicular Cancer
SECTION H: GYNECOLOGICAL
84. Cancers ofthe Cervix, Vulva, and Vagina
85. Cancer ofthe Endometrium
86. Ovaries andFallopian Tubes
87. Gestational Trophoblastic Disease
88. Cancer ofthe Breast
SECTION I: SARCOMAS
89. Sarcomas of Bone
90. Sarcomas of Soft Tissue
SECTION J
91. Carcinoma of Unknown Primary
SECTION K: PEDIATRICS
92. Pediatric SolidTumors
93. Childhood Leukemia
94. Childhood Lymphoma
SECTION L: HEMATOLOGICAL
95. Acute Leukemiasin Adults
96. Myelodysplastic Syndromes
97. Myeloproliferative Disorders
98. Chronic MyeloidLeukemia
99. Chronic LymphoidLeukemias
100. Hairy CellLeukemia
101. Multiple Myelomaand Related Disorders
102. Hodgkins Lymphoma
103. Non-Hodgkin Lymphoma
104. Cutaneous T-Cell Lymphoma andCutaneous B-Cell Lymphoma
105. Adult T-CellLeukemia-Lymphoma
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