STROKE. PATHOPHYSIOLOGY, DIAGNOSIS AND MANAGEMENT (DIGITAL VERSION INCLUDED)

DESCRIPTION

Authored by theworlds foremost stroke experts this classic textbrings you fully up to date with current researchfindings and management approaches for cerebrovascular disease. Stroke: Pathophysiology Diagnosisand Management 7th Edition covers everyaspect of this fast-movingfield and is an ideal resourcefor stroke specialists general neurologists and other medical professionals with an interest in stroke. Youll find expert clinicalguidance comprehensive pathophysiology coverage data from recent trialsadvances in diagnostictests full-color CT images pathologyslides and much more for a complete picture of todaysstroke medicine.

·       Helps you recognize theclinical manifestations of stroke, use the latest laboratoryand imaging studies to arriveat a diagnosis, and generatean effective medical and surgical treatmentplan.

·       Keeps you abreast ofthe overwhelming volume of studiesand guidelines in this dynamic field,providing clear summaries and practicalevaluations of all relevant data.

·       Contains updates throughout, including the latestclinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies,and the newguidelines from the ASA.

·       Includes new slides forlectures, covering basic science, case studies, and interventionaltreatment overviews.

·       Features a Key Points summaryat the beginning of each chapterso you can quickly find important information.

·       Provides abundant full-color CT images and pathology slidesthat help you make efficientand accurate diagnoses.

·       Enhanced eBook version included with purchase. Your enhanced eBook allows you toaccess all of the text,figures, and references from the bookon a variety of devices.

TABLE OF CONTENTS

Section 1Pathophysiology
Introduction
1. Cerebral Vascular Biology in Health and Disease
2. Mechanisms of Thrombosis and Thrombolysis
3. Cerebral Blood Flow and Metabolism: Regulation and Pathophysiology inCerebrovascular Disease
4. Histopathology of Brain Tissue Response to Stroke andInjury
5. Molecular and Cellular Mechanisms ofIschemia-Induced Neuronal Death
6. Intracellular Signaling: Mediators and Protective Responses
7. The Neurovascular Unit and Responses to Ischemia
8. Mechanisms of Damage After CerebralHemorrhage
9. White Matter Pathophysiology
10. Cerebral Ischemia and Inflammation
11. Mechanisms of Plasticity, Remodeling and Recovery
12. Genetics and Vascular Biology of Brain VascularMalformations
13. Gliovascular Mechanisms and White Matter Injury inVascular Cognitive Impairment and Dementia
Section 2 Epidemiology and Risk Factors
Introduction
14. Global Burden of Stroke
15. Stroke Disparities
16. Risk Factors and Prevention
17. Prognosis after Stroke
18. Vascular Dementia and Cognitive Impairment
19. Genetic Basis of Stroke Occurrence, Prevention and Outcome
Section 3 Clinical Manifestations
Introduction
20. Classification of Ischemic Stroke
21. Clinical Scales to Assess Patients with Stroke
22. Carotid Artery Disease
23. Anterior Cerebral Artery Disease
24. Middle Cerebral Artery Disease
25. Posterior Cerebral Artery Disease
26. Vertebrobasilar Disease
27. Lacunar Syndromes, Lacunar Infarcts, and CerebralSmall-Vessel Disease
28. Intracerebral Hemorrhage
29. Aneurysmal Subarachnoid Hemorrhage
30. Arteriovenous Malformations and Other VascularAnomalies
31. Stroke and Other Vascular Syndromes of the SpinalCord
Section 4 Specific Conditions and Stroke
Introduction
32. Cardiac Diseases
33. Atherosclerotic Disease of the Proximal Aorta
34. Stroke Related to Surgery and Other Procedures
35. Arterial Dissection, Fibromuscular Dysplasia, and CarotidWeb
36. Inflammatory and Infectious Vasculopathies
37. Reversible Cerebral Vasoconstriction Syndromes
38. Posterior Reversible Encephalopathy Syndrome
39. Stroke and Substance Abuse
40. Moyamoya Disease
41. Cerebral Autosomal Dominant Arteriopathy with SubcorticalInfarcts and Leukoencephalopathy
42. Hematologic Disorders and Stroke
43. Migraine and Stroke
44. Cryptogenic Stroke
45. Cerebral Venous Thrombosis
Section 5 Diagnostic Studies
Introduction
46. Ultrasonography
47. Computed Tomography-Based Evaluation ofCerebrovascular Disease
48. Magnetic Resonance Imaging of CerebrovascularDiseases
49. Cerebral Angiography
50. OMICs in Stroke: Insight into stroke through epigenomics,transcriptomics, proteomics, lipidomics, and metabolomics
Section 6 Therapy
Part A: Medical Therapy
Introduction
51. Stroke Systems of Care and Impact on Acute StrokeTreatment
52. Prehospital and Emergency Department Care of thePatient with Acute Stroke
53. Intravenous Thrombolysis
54. Antithrombotic Therapy for Treatment of AcuteIschemic Stroke
55. General Stroke Management and Stroke Units
56. Critical Care of the Patient with Acute Stroke
57. Pharmacologic Modification of Acute CerebralIschemia
58. Treatment of "Other" Stroke Etiologies
59. Medical Therapy of Intracerebral andIntraventricular Hemorrhage
60. Rehabilitation and Recovery of the Patient withStroke
61. Interventions to Improve Recovery after Stroke
62. Enhancing Stroke Recovery with Cellular Therapies
63. Antiplatelet Therapy for Secondary Prevention ofStroke
64. Secondary Prevention of Cardioembolic Stroke
65. Design of Stroke-Related Clinical Trials
Part B: Interventional Therapy
Introduction
66. Endovascular Therapy of Extracranial and IntracranialOcclusive Disease
67. Endovascular Treatment of Acute Ischemic Stroke
68. Endovascular Treatment of Intracranial Aneurysms
69. Interventional Therapy of Brain and SpinalArteriovenous Malformations
70. Dural Arteriovenous Malformations
Part C: Surgical Therapy
Introduction
71. Surgery of Anterior and Posterior Aneurysms
72. Surgery for Intracerebral Hemorrhage
73. Management of Intraventricular Hemorrhage
74. Surgical Management of Cranial and SpinalArteriovenous Malformations
75. Surgical Management of Cavernous Malformations andVenous Anomalies
76. Indications for Carotid Endarterectomy in Patientswith Asymptomatic and Symptomatic Carotid Stenosis
77. Extracranial to Intracranial Bypass for CerebralIschemia
78. Decompressive Craniectomy for Infarction and Hemorrhage