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Known forits clear readability thorough coverage and expert authorship Murray & Nadels Textbook of Respiratory Medicine has long beenthe gold standard text in the fast-changing field of pulmonary medicine. The new 7thEdition brings you fully up to date with newly expandedcontent numerous new chapters a new editorial team and extensive updates throughout. It covers the entirespectrum of pulmonology in one authoritative point-of-care reference making it anideal resource for pulmonary physicians fellows and other pulmonary practitioners.
Offers definitive,full-color coverage of basicscience, diagnosis, evaluation,and treatment of the full rangeof respiratory diseases.
Provides detailedexplanations of each disease entity and differential diagnoses with state-of-the-art, evidence-basedcontent by global leadersin the field.
Contains a newlyexpanded section on common presentations of respiratory disease, plus new chapters on COVID-19, asthma and obesity, airplane travel, lung cancer screening,noninvasive support of oxygenation,lung microbiome, thoracic surgery, inhaled substances, treatment of lung cancer, and more.
Covers hot topicssuch as vaping; advanced ultrasound applications and procedures; interventional pulmonology; immunotherapy; lung cancer targetedtherapy; outbreaks, pandemics and bioterrorism; point-of-care ultrasound;use of high-flow oxygen, and more.
Includes extensivelyreorganized sections on basic science, pleural disease, and sleep, with new chaptersand approaches to the topics.
Features more than1,450 anatomic, algorithmic,and radiologic images (400are new!) including CT,PET, MR, and HRCT, plus extensive online-only content: 200 procedural and conceptual videos plus audio clips of lung sounds.
Brings youup to date with the latest respiratory drugs, mechanisms of action, indications, precautions, adverse effects, and recommendations, with increased emphasis on algorithms to illustrate decisionmaking.
Enhanced eBook versionincluded with purchase. Your enhanced eBook allows you access toall of the text, figures, reporting templates, and references from the book on a variety of devices.
Edited by V.CourtneyBroaddus, MD, Professor Emeritus of Medicine Universityof California, San Francisco Division of Pulmonaryand Critical Care MedicineSan Francisco General Hospital San Francisco, California ; Joel D Ernst, MD, Professor and Chief Division of Experimental Medicine Departmentof Medicine University of California, San FranciscoSan Francisco General Hospital San Francisco, California ; Talmadge E King, Jr, MD, Julius R. Krevans Distinguished Professorship in InternalMedicine, Chair, Departmentof Medicine, University of California San Francisco,San Francisco, California; Stephen C. Lazarus, MD, Professor ofMedicine, Division of Pulmonary & Critical Care Medicine, Director,Clinical Training Program in Pulmonary& Critical CareMedicine, Associate Director, Adult Pulmonary Laboratory, Senior Investigator,Cardiovascular Research Institute,University of California San Francisco, SanFrancisco, California ; Kathleen F.Sarmiento , MD, Associate ProfessorDepartment of Medicine Universityof California, San Francisco ; Lynn M. Schnapp, MD; Renee D Stapleton, MD, PhD, Associate Professor, Pulmonary and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont and MichaelB. Gotway, MD, Professor ofRadiology, Mayo Clinic, Scottsdale, AZ; Clinical AssociateProfessor, Diagnostic Radiology/ Biomedical Imaging & Pulmonary / Critical Care Medicine, Department of Radiology, University ofCalifornia, San Francisco, San Francisco, California; Clinical Professor, University of Arizona College of Medicine, Phoenix, AZ; AdjunctProfessor, Department of Biomedical Informatics, Arizona State University, Tempe, AZ
INDEX
PART 1 SCIENTIFIC PRINCIPLES OF RESPIRATORY MEDICINE
SECTION A Anatomy and Development of the Respiratory Tract
1. Anatomy
2. Lung Growthand Development
3. Alveolar Compartment
4. Airway Biology
5. Lung Mesenchyme
6. Vascular Biology
7. Lymphatic Biology
8. Regeneration and Repair
9. Genetics of LungDisease
SECTION B Respiratory Physiology
10. Ventilation, Blood Flow, and Gas Exchange
11. Respiratory System Mechanics and Energetics
12. Acid-Base Balance
13. Aerosol and Drug Delivery
14. Pleural Physiology and Pathophysiology
SECTION C Defense Mechanisms and Immunology
15. Innate Immunity
16. Adaptive Immunity
17. Microbiome
PART 2 DIAGNOSIS AND EVALUATION OF RESPIRATORY DISEASE
SECTION D Diagnosis
18. History and Physical Examination
19. Microbiological Diagnosis of Lung Infection
20. Thoracic Radiology:Noninvasive Diagnostic Imaging
21. Thoracic Radiology:Invasive Diagnostic Imagingand Image-Guided Interventions
22. Pathology
23. Ultrasonography: Principles, and Basic Thoracicand Vascular Imaging
24. Ultrasonography: Advanced Applications and Procedures
25. Positron EmissionTomography
26. Diagnostic Bronchoscopy: BasicTechniques
27. Diagnostic Bronchoscopy:Advanced Techniques (EBUS and Navigational)
28. Therapeutic Bronchoscopy: Interventional Techniques
29. Thoracoscopy
30. Thoracic Surgery
SECTION E Evaluation
31. Pulmonary FunctionTesting: Physiologic and technical principles
32. Pulmonary FunctionTesting: Interpretation andApplications
33. Exercise Testing
34. Preoperative Evaluation
35. Evaluation of Respiratory Impairment and Disability
PART 3 CLINICAL RESPIRATORY MEDICINE
SECTION F Evaluation of Common Presentations of Respiratory Disease
36. Dyspnea
37. Cough
38. Chest Pain
39. Wheezing and Stridor
40. Hemoptysis
41. Pulmonary Nodule
42. Positive Screening Test for Tuberculosis
43. Aspiration
44. Hypoxemia
45. Hypercarbia
SECTION G Infectious Diseases of the Lungs
46. Community-AcquiredPneumonia
46a. COVID-19
47. Influenza
48. Hospital-Acquired Pneumonia
49. Ventilator-AssociatedPneumonia
50. Lung Abscess
51. Tuberculosis: Epidemiology andPrevention
52. Tuberculosis: Pathogenesis andimmunity
53. Tuberculosis: Clinical Manifestationsand Diagnosis
54. Tuberculosis: Treatment ofDrug-Susceptible and Drug-Resistant
55. Nontuberculous Mycobacterial Infections
56. Fungal Infections:Endemic
57. Fungal Infections:Opportunistic
58. Parasitic Infections
59. Outbreaks, Epidemics,and Bioterrorism
SECTION H Obstructive Diseases
60. Asthma: Pathogenesisand Phenotypes
61. Asthma and Obesity
62. Asthma: Diagnosis and Management
63. COPD: Pathogenesis and NaturalHistory
64. COPD: Diagnosis and Management
65. Smoking Hazards:Cigarettes, Vaping, Marijuana
66. Smoking Cessation
67. Cystic Fibrosis: Pathogenesis and Epidemiology
68. Cystic Fibrosis: Diagnosis andManagement
69. Bronchiectasis
70. Upper AirwayDisorders
71. Large AirwayDisorders
72. Bronchiolitis
SECTION I Neoplasms of the Lung
73. Lung Cancer:Molecular Biology and Targets
74. Lung Cancer:Epidemiology
75. Lung Cancer:Screening
76. Lung Cancer:Diagnosis and Staging
77. Lung Cancer:Treatment
78. Rare PrimaryLung Tumors
79. Metastatic MalignantTumors
80. Benign LungTumors
SECTION J Disorders of the Pulmonary Circulation
81. Pulmonary Thromboembolism:Presentation and Diagnosis
82. Pulmonary Thromboembolism:Prophylaxis and Treatment
83. Pulmonary Hypertension:General Approach
84. Pulmonary Arterial Hypertension: Group 1
85. Pulmonary Hypertensiondue to LungDisease: Group 3
86. Pulmonary Hypertensiondue to ChronicThromboembolic Disease: Group 4
87. Pulmonary Vasculitis
88. Pulmonary Vascular Anomalies
SECTION K Infiltrative and Interstitial Lung Diseases
89. Idiopathic PulmonaryFibrosis
90. Nonspecific Interstitial Pneumonitis and Other Idiopathic Interstitial Pneumonias
91. Hypersensitivity Pneumonitis
92. Connective TissueDiseases
93. Sarcoidosis
94. Diffuse Alveolar Hemorrhage
95. Pulmonary LangerhansCell Histiocytosis and other Rare DiffuseInfiltrative Lung Diseases
96. Eosinophilic Lung Diseases
97. Lymphangioleiomyomatosis
98. Pulmonary Alveolar Proteinosis Syndromes
99. Drug-Induced Pulmonary Disease
SECTION L Environmental and Occupational Hazards
100. Asthma in the Workplace
101. Pneumoconioses
102. Indoor and Outdoor Air Pollution
103. Acute Responses to Toxic Exposures
104. Trauma and Blast Injuries
105. High Altitude
106. Air Travel
107. Diving Medicine
SECTION M Disorders of the Pleura
108. Pleural Effusions
109. Pleural Infections
110. Pneumothorax
111. Chylothorax
112. Pleural Fibrosis and UnexpandableLung
113. Hemothorax
114. Pleural Malignancy
SECTION N Disorders of the Mediastinum
115. Mediastinal Tumors and Cysts
116. Mediastinitis and Fibrosing Mediastinitis
SECTION O Disorders of Sleep and Control of Breathing
117. Control of Breathing and Upper Airways DuringSleep
118. Consequences of Sleep Disruption
119. Sleep-DisorderedBreathing: General Approach
120. Obstructive Sleep Apnea
121. Central Sleep Apnea
122. Sleep-DisorderedBreathing: Treatment
SECTION P Respiratory Manifestations of Extrapulmonary Disorders
123. Pulmonary Complicationsof HIV Infection
124. Pulmonary Complicationsof Primary Immunodeficiencies
125. Pulmonary Complicationsof Stem Cell and Solid Organ Transplantation
126. Pulmonary Complicationsof Abdominal Diseases
127. Pulmonary Complicationsof Hematologic Diseases
128. Pulmonary Complicationsof Endocrine Diseases
129. The Lungs in Obstetric and Gynecologic Diseases
130. The Respiratory System and Neuromuscular Diseases
131. The Respiratory System and Chest Wall Diseases
SECTION Q Management of Respiratory Failure
132. Acute VentilatoryFailure
133. Pulmonary Edema
134. Acute RespiratoryDistress Syndrome
135. Mechanical Ventilation
136. Noninvasive Support of Ventilation
137. Noninvasive Support of Oxygenation
138. Extracorporeal Support of GasExchange
139. Pulmonary Rehabilitation
140. Lung Transplantation
141. End-of-LifeCare in Respiratory Failure
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